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Updated January 30, 2002
Can the OTC cough medicine DM be addictive?

Ask Dr. Bill

Dear Dr. Bill,
I have been giving my teen-age son an over-the-counter cough medicine containing "DM." It has been working well but my neighbor tells me that he could become addicted to it. Is this true? I've been giving it to my kids for years.

Worried Mom - Teaneck

 

Dear Worried Mom,
Assuming that you are giving the medicine to your son at the indicated dose, you needn't be terribly concerned. On the other hand, in a report published in the news bulletin of the American Society of Addiction Medicine last year (Drug Trends: DM: A Store-Bought Dissociative?" Bobo, W.V.,Miller,S.C., Jackson,J,et.al., ASAM News, Jan-Feb,2001), warns that there is apparently good reason to advise physicians; drug and alcohol counselors; educators and parents to educate themselves about the dangers of the intentional misuse of DM.

To borrow heavily from that report: Dextromethorphan (DM) is used in more than 50 OTC cough remedies. At indicated doses, DM safely and effectively inhibits the brain's cough centers to approximately the same extent as opiates, such as codeine, but without other negative opioid effects (analgesia, CNS depression,etc.). However, at excessive doses, intentional or recreational, a toxic syndrome may emerge despite early reports indicating a total lack of CNS effects or addiction potential. Authorities now warn that DM carries a significant addiction potential, and that abuse of this seemingly benign cough medicine has become increasingly popular among adolescents and young adults. The National Clearinghouse on Alcohol and Drug Information (NCADI) recently added DM to its list of other addictive dissociative agents, such as ketamine and PCP, each of which, within 15 to 30 minutes of ingestion, can cause effects such as increased perceptual awareness, altered time perception, hyper-excitability, pressure of thought and disorientation.

The DM "high" may last anywhere from 3 to 6 hours. Such effects require the ingestion of large amounts of the substance, with doses estimated as ranging from 300 to 1,800 mg/kg (more than 100 times the amount in a normal prescribed dose). This translates to over 4 ounces of DM-containing cough syrup, prompting some abusers to ingest the drug in a concentrated powder form which is reportedly available both on the street and on the Internet.

As with the better-known drugs of abuse, users of DM have developed a social culture around the drug over the past 30 years. Popular street names include "DM," "DXM," "DMX," "Skittles," "Vitamin D," "Dex," "Tussin" or "Robo." Numerous internet sites dedicated to the misuse of DM further this cultural movement by explaining how to acquire the drug, either directly through mail order or by chemical extraction. Some of these sites also display the artwork of artists who use DM to "enhance their creative expression" in ways similar to the early users of LSD and other hallucinogens. DM has been distributed at dance parties or "raves," where there is open use and sale of other psychoactive agents as well.

There is very little data are available to report the extent of DM abuse. While it appears that the drug has become especially popular among adolescents, it is likely that the social impact of the problem has yet to be fully investigated. There are relatively few deterrents to abusing DM by prospective and active users. ....It is an inexpensive, legal product that is available over-the-counter to any age group. Because it is produced by pharmaceutical companies, abusers may believe it is safer to use than the illicit drugs, or even legal substances such as nicotine and alcohol, both of which come with Surgeon General warnings. Further, DM is not among the substances routinely tested for on urinary or serologic toxicology screens, and the legal consequences of a positive drug screen for DM are questionable at best. Individuals who test positive could claim that they are simply self-medicating for a cough. In short, A WARNING: DM has many characteristics that make it an attractive choice for adolescents who experiment with drugs.


Dr. Willian Van Ost, M.D., is a Co-founder of The Van Ost Institute for Family Living, a non-profit outpatient center for treatment of addictive illnesses. Located in Englewood, it offers continuing, free weekly educational lectures. (Call 201-569-6667, e-mail to vanost@msn.com or visit www.vanostinstitute.org). Dr. Bill welcomes questions about addiction and effects on the family.

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Address inquiries:
Dr. Bill
Care of The Van Ost Institute
150 East Palisade Ave.
Englewood, NJ 07631-3010
Phone inquiries: (201) 569-6667
E-mail to: drbill@vanostinstitute.org

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